Found 38 matching trials
Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure PHASE4 The purpose of this study is to evaluate the effects of spironolactone on c...
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Multiple Locations
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Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease PHASE2 Vascular endothelial dysfunction increases cardiovascular (CV) risk and con...
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Hypertension Research Clinic at UAB
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Dapagliflozin With or Without Spironolactone for HFpEF PHASE2 Heart failure (HF) is a condition in which the heart does not contract ("pu...
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Unidade Local de Saúde Gaia/Espinho
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Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF) PHASE4 The purpose of this study is to evaluate the effects of spironolactone and ...
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Multiple Locations
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Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden PHASE3 The aim of the study is to evaluate the effect of antifibrotic therapy on r...
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University Medical Center Göttingen
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Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure PHASE2 The primary objective of this study is to test the hypothesis that high-dos...
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Emory University School of Medicine
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Importance of Aldosterone in the Pathogenesis of Hypertensive Heart Disease PHASE3 The Renin-Angiotensin-Aldosterone-system is important in the development of...
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University Erlangen-Nürnberg, Nephrology and Hypertension
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Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy PHASE4 Hypertrophic Cardiomyopathy (HCM) is the most common genetic cardiomyopathy...
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Tufts Medical Center
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Optimum Treatment for Drug-Resistant Hypertension PHASE4 This study was recommended by NICE, as part of its 2006 guidance for the tr...
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Adjuvant Anti-Mineralocorticoid-Receptor Treatment in Anti-VEGF Refractory Neovascular Age-Related Macular Degeneration PHASE2 Prospective, non-comparative, mono-center pilot study. Patients with neovas...
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Multiple Locations
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